Genetic Disorders in Arabs

qayee bio human baff r

• Djoumana
• November 26, 2021
• 0

The ELISA gear relies on commonplace sandwich enzyme-linked immune-sorbent assay expertise. A monoclonal antibody from mouse specific for BAFF-R has been pre-coated onto 96-well plates. Requirements (Expression system for common: NSO; Immunogen sequence: S7-A71) and try samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for BAFF-R is added subsequently after which adopted by washing with PBS or TBS buffer.

Avidin-Biotin-Peroxidase Subtle is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualise HRP enzymatic response. TMB is catalyzed by HRP to supply a blue shade product that turned yellow after along with acidic cease reply. The density of yellow is proportional to the Human BAFF-R quantity of pattern captured in plate.

Key decisions and particulars

• Sensitivity: 10 pg/ml
• Differ: 78 pg/ml – 5000 pg/ml
• Pattern kind: Cell customized supernatant, Cell Lysate, EDTA Plasma, Hep Plasma, Serum
• Detection method: Colorimetric
• Assay kind: Sandwich (quantitative)
• Reacts with: Human

• Product set up

  Human BAFF-R ELISA Instruments

• Detection method

  Colorimetric

• Precision

  Intra-assay

  Pattern	n	Point out	SD	CV%
  1	16	147pg/ml	10.29	= 7%
  2	16	683pg/ml	49.85	= 7.3%
  3	16	2750pg/ml	206.25	= 7.5%

  Inter-assay

  Pattern	n	Point out	SD	CV%
  1	24	156pg/ml	13.88	= 8.9%
  2	24	700pg/ml	62.3	= 8.9%
  3	24	2531pg/ml	227.05	= 8.9%

• Pattern kind

  Cell customized supernatant, Serum, Cell Lysate, Hep Plasma, EDTA Plasma

• Assay kind

  Sandwich (quantitative)

• Sensitivity

  < 10 pg/ml

• Differ

  78 pg/ml – 5000 pg/ml

• Assay time

  3h 30m

• Assay dimension

  Loads of steps commonplace assay

• Species reactivity

  Reacts with: Human

• Product overview

  The Human BAFF-R Enzyme-Linked Immunosorbent Assay (ELISA) gear (ab213839) is designed for the quantitative measurement of Human TNFRSF13C in cell customized supernatants, cell lysates, serum and plasma (heparin, EDTA).

  

• Notes

  BAFF-R (moreover generally known as Tumor necrosis problem receptor superfamily member 13C or B-cell-activating problem receptor)  is a protein that in people is encoded by the TNFRSF13C gene. By homology to a BAC clone, the BAFFR gene was mapped to chromosome 22q13.1-q13.31. B-cell activating problem (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell inhabitants. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular phenylalanine-rich area. It’s thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

• Platform

  Pre-coated microplate (12 x Eight appropriately strips)

Rat B-Cell Activating Factor(BAFF)ELISA Kit
QY-E10385	Qayee Biotechnology	96T	EUR 433.2

Mouse B-Cell Activating Factor(BAFF)ELISA Kit
QY-E20186	Qayee Biotechnology	96T	EUR 433.2

Human BAFF-R(CD268)
90103-A	BPS Bioscience	10 µg	EUR 130
Description: Recombinant human BAFF-R (B cell-activating factor from the TNF family), also known as CD268, is a disulfide-linked monomeric protein consisting of 76 a.a. and migrates as an approximately 9 kDa protein under reducing and non-reducing conditions. Optimized DNA sequence encoding human BAFF-R extracellular domain was expressed in E. coli.

Human BAFF-R(CD268)
90103-B	BPS Bioscience	50 µg	EUR 205
Description: Recombinant human BAFF-R (B cell-activating factor from the TNF family), also known as CD268, is a disulfide-linked monomeric protein consisting of 76 a.a. and migrates as an approximately 9 kDa protein under reducing and non-reducing conditions. Optimized DNA sequence encoding human BAFF-R extracellular domain was expressed in E. coli.

BAFF-R(human):Fc(human)
BC-323	Kamiya Biomedical Company	50 ug	EUR 667

[Cys0]-BAFF-R (159-183) (Mouse) / [Cys0]-BAFF-R (151-175) (Human)
030-51	PHOENIX PEPTIDE	100 μg	EUR 177.12

BAFF Receptor Antibody / BAFF-R
RQ4381	NSJ Bioreagents	100 ug	EUR 356.15
Description: Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.

Baff receptor Antibody / Baff-r
RQ4338	NSJ Bioreagents	100 ug	EUR 356.15
Description: Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.

[Cys0]-BAFF-R (159-183) (Mouse) / [Cys0]-BAFF-R (151-175) (Human) - Antibody
H-030-51	PHOENIX PEPTIDE	50 μl	EUR 604.8

Recombinant Human BAFF-R (TNFRSF13C)
Z100015	ABM	50 µg	EUR 105
Description: The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.

Recombinant Human BAFF-R (TNFRSF13C)
Z100017	ABM	100 µg	EUR 215
Description: The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.

Recombinant Human BAFF-R (TNFRSF13C)
Z100019	ABM	1.0 mg	EUR 1060
Description: The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.

[Cys0]-BAFF-R (108-129) (Human)
030-52	PHOENIX PEPTIDE	100 μg	EUR 177.12

Human BAFF-R Protein, mFc Tag
E33P100044	EnoGene	10 μg	EUR 225

Human BAFF-R Protein, hFc Tag
E33P100503	EnoGene	10 μg	EUR 225

BAFF-R Antibody
3578R-100	Biovision	each	EUR 379.2

BAFF-R Antibody
3578R-30T	Biovision	each	EUR 175.2

BAFF-R Antibody
R30462	NSJ Bioreagents	100 ug	EUR 356.15
Description: Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFF-R, is a protein in humans is encoded by the TNFRSF13C gene. The gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.

[Cys0]-BAFF-R (159-183) (Mouse) / [Cys0]-BAFF-R (151-175) (Human) - Purified IgG Antibody
G-030-51	PHOENIX PEPTIDE	200 μg	EUR 604.8

Bio Bucket™ collapsible laboratory ice bucket, 5 Liter, 1/each
B8300	MTC Bio	1/pack	EUR 54
Description: Bio Bucket

Human tenascin-R(TN-R)ELISA Kit
QY-E00282	Qayee Biotechnology	96T	EUR 433.2

Biotinylated Recombinant Human TNFRSF13C/BAFF-R/CD268 Protein
RP02582	Abclonal	1000μg	EUR 422.5

BAFF-R Blocking Peptide
3578RBP-50	Biovision	each	EUR 183.6

BAFF-R Recombinant Protein
90-237	ProSci	50 ug	EUR 600.9
Description: BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation . Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome , Rheumatoid Arthritis (RA) , Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE) . BAFF is also increased levels in some lymphoid cancers.

BAFF-R Polyclonal Antibody
3578-100	Biovision	each	EUR 379.2

Polyclonal BAFF-R Antibody
APR15125G	Leading Biology	0.1mg	EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BAFF-R . This antibody is tested and proven to work in the following applications:

PE anti-human CD268 (BAFF-R)
E16FHP268-025	EnoGene	25 tests	EUR 476.67
Description: Available in various conjugation types.

PE anti-human CD268 (BAFF-R)
E16FHP268-100	EnoGene	100 tests	EUR 1083.33
Description: Available in various conjugation types.

APC anti-human CD268 (BAFF-R)
E16FHA268-100	EnoGene	100 tests	EUR 1083.33
Description: Available in various conjugation types.